Yes, it's just two 2.1s. The only down side is you'd have two volume controllers, one for front/one for rear, but you can always just use your soundcard software to adjust volume.
You'll also need to do some arranging so both volume controllers are attached to the front speakers. They are not hardwired onto the speaker--they slide out backwards and can be mounted to any speaker.
I'm sure I just confused you now--feel free to send me an email if you need further help:
amy.unger@klipsch.com